Phylogeography can be defined as the study of the distribution of genetic lineages within a phylogenetic reconstruction aiming at understanding the genetic history of a specific organism. Here I will show you a few examples of the application of phylogeographic tools, genetic and epidemiological data in order to understand and correlate the geographical dispersal of pathogenic microorganisms.
This includes recent work on SARS-CoV-2, on mycobacteria (Mycobacterium tuberculosis and Mycobacterium bovis) and I will share a couple of preliminary ideas on a nosocomial infectious pathogen, Klebsiella pneumoniae. I will show that, beyond the understanding of the evolutionary history of the pathogen, phylogeographic approaches can be used to identify potential clusters of infection in public health, lineages that underwent acquired resistance to drugs, lineages with increasing spreading rate and the effect of public health measures in the spread of these pathogens.
11 Jan - 12:00h |
