Mammalian and yeast as complementary cell models in orogrammed cell death

The course will include the theoretical modules referred above and a hands-on intensive module of lab work. In addition to brief descriptive lectures, the theoretical modules will entail case study and topic or problem–driven group discussions.

GENERAL INFORMATION
The course will include the theoretical modules referred above and a hands-on intensive module of lab work. In addition to brief descriptive lectures, the theoretical modules will entail case study and topic or problem?driven group discussions. The hands-on lab module will illustrate different aspects of the theoretical sessions topics, and will include different techniques to monitor morphological, biochemical and molecular changes associates to cell death processes namely, epifluorescence microscopy and flow cytometry. They will be followed by results interpretation, group discussion and final wrap up.

COORDINATORS
Manuela Côrte-Real, Maria João Sousa
CBMA-DB, Universidade do Minho, PORTUGAL

VENUE
Departamento de Biologia, Universidade do Minho
July 4-15

LECTURERS
Muriel Priault CNRS- Université de Bordeaux, France
Nadine Camougrand CNRS- Université de Bordeaux, France
Stéphen Manon CNRS- Université de Bordeaux, France
Campbell Gourlay Cell and Developmental Biology, Univeristy of Kent, UK
M. Helena Vasconcelos Meehan Faculty of Pharmacy and IPATIMUP, University of Porto, Portugal
Cecília Rodrigues Molecular Pathogenesis Centre, Faculty of Pharmacy, University of Porto, Portugal
Lucília Saraiva Faculty of Pharmacy, University of Porto, Portugal
Ana Preto CBMA-DB, University of Minho, Portugal
Olga Coutinho CBMA-DB, University of Minho, Portugal
Rui Silva CBMA-DB, University of Minho, Portugal
Sara Alves CBMA-DB, University of Minho, Portugal
Manuela Côrte-Real CBMA-DB, University of Minho, Portugal
Maria João Sousa CBMA-DB, University of Minho, Portugal

TOPICS

1. Programmed Cell Death processes versus necrosis
2. Apoptosis
3. Programmed necrosis
4. Autophagy
5. Autophagy in physiology and pathology
6. Mitophagy: from yeasts to mammalian cells
7. The central role of mitochondria in the intrinsic apoptotic pathway: mitochondrial membrane permeabilization mechanisms
8. The cytoskeleton and apoptosis
9. Utilization of yeast to study the molecular aspects of the function of Bcl-2 family members
10. A role for actin in regulating apoptosis/programmed cell death: evidence spanning yeast, plants and animals
11. Yeast as a tool for anticancer drug research
12. Regulation of Bax by Mammalian Protein Kinase C
13. The role of human oncogene KRAS in autophagy regulation: Saccharomyces cerevisiae as a model
14. Features of Cell Death in Neurodegenerative Diseases
15. Regulation of Programmed Cell Death in Cancer and its Pharmacological Modulation

PROGRAM (coming soon)

CONTACTS AND INFORMATIONS
Manuela Côrte-Real - This email address is being protected from spambots. You need JavaScript enabled to view it.
Maria João Sousa - This email address is being protected from spambots. You need JavaScript enabled to view it.

Centro de Biologia Molecular e Ambiental
Departamento de Biologia, Universidade do Minho
Campus de Gualtar 4710-054 Braga
PORTUGAL
Phone +351 253 604310
Fax +351 253 678980


DETAILS FOR REGISTRATION
Maximum Number of Participants: N/A
Registration Deadline: N/A
Registration fee: N/A € (Classes) or N/A € (Classes + Practices)

Click here to register for the course

After registration, please contact Prof. Maria João Sousa to proceed to payment.

After paying, send a copy of the receipt of transfer to the email mentioned above as proof of payment. Registration is confirmed after payment.

mais informações: http://cbma.bio.uminho.pt/index.php?option=com_content&view=article&id=207&Itemid=106